SCHEMBL19901160

SCHEMBL19901160

Cc1ccc2c(oc3ccccc32)c1N1CN(C)c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.34
LMNA P02545 4/20 0.33
MAPK1 P28482 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HRH4 Q9H3N8 2/20 0.33
TP53 P04637 2/20 0.33
MAOA P21397 1/20 0.33
MEN1 O00255 5/20 0.33
KMT2A Q03164 5/20 0.33
ALDH1A1 P00352 5/20 0.33
KDM4E B2RXH2 4/20 0.33
MAPT P10636 3/20 0.33
HPGD P15428 3/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CYP2C19 P33261 1/20 0.32
TSHR P16473 2/20 0.32
CYP1A2 P05177 1/20 0.32
HSD17B10 Q99714 1/20 0.31
PPARG P37231 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19901107 0.86 TSHR (0.37) LMNAMAPK1SMN1; SMN2HRH4TP53
SCHEMBL19901133 0.86 TSHR (0.37) LMNAMAPK1SMN1; SMN2HRH4TP53
SCHEMBL20402560 0.84 PGR (0.33) PGRLMNAMEN1KMT2AALDH1A1
SCHEMBL25562884 0.83 PGR (0.34) PGRLMNAMAPK1SMN1; SMN2HRH4
SCHEMBL18828295 0.83 PIK3CA (0.33) ALDH1A1KDM4ECYP1A2PRKDC
SCHEMBL18054863 0.80 CYP2C9 (0.30)
SCHEMBL26253480 0.77 TSHR (0.36) LMNAMAPK1SMN1; SMN2HRH4TP53
SCHEMBL19901136 0.76 TSHR (0.35) LMNAMAPK1SMN1; SMN2HRH4TP53
SCHEMBL20686998 0.76 PGR (0.36) PGRLMNAMAPK1SMN1; SMN2HRH4
SCHEMBL21758898 0.75 RAB9A (0.32) PGRLMNAMAPK1SMN1; SMN2HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230382935-A1 COMPOUND CONTAINING 1,3-DIKETONE LIGAND AND APPLICATION THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE BEIJING GREEN GUARDEE TECHNOLOGY CO., LTD. (CN) 2023-11-30 US disclosed
EP-3444260-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-02-20 EP disclosed
US-10033000-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-07-24 US disclosed
US-9905784-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10033000-B2 Organic electroluminescent materials and devices LSM8, OPRM1, OXER1 PGR 1869/4885LMNA 354/4885MAPK1 1327/4885
US-20230382935-A1 COMPOUND CONTAINING 1,3-DIKETONE LIGAND AND APPLICATION THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE TLK1, TLK2, PDK3 PGR 2831/4885LMNA 2429/4885MAPK1 417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.