SCHEMBL19901173

SCHEMBL19901173

CCCCC1=CC([Si](C)(C)C2C=C(CCCC)c3ccccc32)c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.39
BCHE P06276 1/20 0.39
PTPN1 P18031 1/20 0.36
HTR6 P50406 3/20 0.35
CNR1 P21554 1/20 0.33
TDP1 Q9NUW8 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP19A1 P11511 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
CHRM2 P08172 1/20 0.30
HTR1A P08908 1/20 0.30
ADRA2A P08913 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD1 P21728 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
ADRA1A P35348 1/20 0.30
OPRM1 P35372 1/20 0.30
DRD3 P35462 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30143298 0.90 HTR6 (0.37) ACHEBCHEHTR6
SCHEMBL21035817 0.87 BCHE (0.33) ACHEBCHEPTPN1HTR6
SCHEMBL29750747 0.78 PPARG (0.32) HTR6
SCHEMBL20943075 0.78 PPARG (0.32) HTR6
SCHEMBL7781755 0.78 HTR6 (0.40) ACHEBCHEHTR6CHRM2HTR1A
Hydrochloric Acid SCHEMBL3678035 0.75 ACHE (0.40) ACHEBCHEPTPN1HTR6CNR1
SCHEMBL20996634 0.75 MEN1 (0.35) ACHEBCHE
SCHEMBL30307379 0.75 MEN1 (0.35) ACHEBCHE
SCHEMBL7544944 0.74 ACHE (0.33) ACHEBCHEHTR6CHRM2HTR1A
SCHEMBL8158527 0.74 ACHE (0.39) ACHEBCHEPTPN1HTR6CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9926395-B2 Hybrid supported metallocene catalyst LG CHEM, LTD. (KR) 2018-03-27 US disclosed
US-9902789-B2 Method for preparing hybrid supported metallocene catalyst LG CHEM, LTD. (KR) 2018-02-27 US disclosed