Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.40 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.31 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28506062 | 0.90 | HTR6 (0.38) | ACHEBCHEHTR6 | |
| Hydrochloric Acid SCHEMBL27520305 | 0.82 | HTR6 (0.33) | ACHEBCHEHTR6CHRM2HTR1A | |
| Hydrochloric Acid SCHEMBL30568155 | 0.79 | ACHE (0.42) | ACHEBCHEPTPN1HTR6CNR1 | |
| Hydrochloric Acid SCHEMBL6466704 | 0.79 | HTR6 (0.35) | HTR6 | |
| Hydrochloric Acid SCHEMBL5599308 | 0.79 | ACHE (0.42) | ACHEBCHEPTPN1HTR6CNR1 | |
| Hydrochloric Acid SCHEMBL27499718 | 0.79 | ACHE (0.39) | ACHEBCHEPTPN1HTR6CNR1 | |
| Hydrochloric Acid SCHEMBL910832 | 0.78 | HTR6 (0.46) | HTR6 | |
| Hydrochloric Acid SCHEMBL6907085 | 0.76 | BCHE (0.37) | ACHEBCHEPTPN1HTR6CNR1 | |
| SCHEMBL8158527 | 0.75 | ACHE (0.39) | ACHEBCHEPTPN1HTR6CNR1 | |
| SCHEMBL19901173 | 0.75 | ACHE (0.39) | ACHEBCHEPTPN1HTR6CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118223194-A | Soft and durable nonwoven web | 金伯利-克拉克环球有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-116728919-A | Laterally extensible nonwoven composites | 金伯利-克拉克环球有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-105722485-B | Absorbent article comprising a soft and durable backsheet | 金伯利-克拉克环球有限公司 | 2020-02-11 | — | — | CN | disclosed |
| EP-2028198-B1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containinig the same | IDEMITSU KOSAN CO (JP) | 2010-01-06 | — | — | EP | disclosed |
| EP-1865006-B1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU KOSAN CO (JP) | 2009-06-24 | — | — | EP | disclosed |
| EP-1865005-A2 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | Idemitsu Kosan Co., Ltd. (JP) | 2007-12-12 | — | — | EP | disclosed |
| EP-1561762-A1 | PROCESS FOR PRODUCING PROPYLENE/ETHYLENE BLOCK COPOLYMER AND PROPYLENE/ETHYLENE BLOCK COPOLYMER | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2005-08-10 | — | — | EP | disclosed |
| US-20050159566-A1 | improved flexibility, and transparency, heat sealability and hot tackiness; good softness, a less stickiness, and an good compatibility with polyolefin resins; for sanitary materials, packing, bookbinding, fibers | IDEMITSU KOSAN CO., LTD (JP) | 2005-07-21 | — | — | US | disclosed |
| US-6794476-B2 | Propylene homopolymer and propylene copolymer | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2004-09-21 | — | — | US | disclosed |
| US-20020198350-A1 | Propylene homopolymer and propylene copolymer | IDEMITSU KOSAN CO. LTD. (JP) | 2002-12-26 | — | — | US | disclosed |