Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466889 | 0.83 | TOP2A (0.32) | — | |
| SCHEMBL8468840 | 0.83 | HTR6 (0.39) | HTR6 | |
| SCHEMBL7546253 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL8680298 | 0.81 | TOP2A (0.30) | — | |
| SCHEMBL7944622 | 0.78 | GPR3 (0.34) | GPR3HTR2A | |
| SCHEMBL30143298 | 0.77 | HTR6 (0.37) | ACHEBCHEHTR6 | |
| SCHEMBL19901173 | 0.74 | ACHE (0.39) | ACHEBCHECHRM2HTR1AADRA2A | |
| SCHEMBL5175634 | 0.74 | GPR3 (0.46) | ACHEBCHEGPR3HTR2ACHRM2 | |
| SCHEMBL21035817 | 0.73 | BCHE (0.33) | ACHEBCHEHTR6 | |
| Hydrochloric Acid SCHEMBL6559588 | 0.70 | GPR3 (0.43) | ACHEBCHEGPR3HTR2ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693497-B1 | Process for the preparation of silicon-bridged asymmetric cyclopentadienyl-, indenyl- and fluorenyl-containing ligand systems | BOREALIS TECH OY (FI) | 2002-06-12 | — | — | EP | disclosed |
| EP-0693497-A2 | Process for the preparation of silicon-bridged asymmetric cyclopentadienyl-, indenyl- and fluorenyl-containing ligand systems | PCD-Polymere Gesellschaft m.b.H. (AT) | 1996-01-24 | — | — | EP | disclosed |