Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28836071 | 0.88 | KDM4E (0.33) | KDM4EALDH1A1TDP1KIF11MAPT | |
| SCHEMBL8496183 | 0.86 | KDM4E (0.34) | KDM4EALDH1A1TDP1KIF11MAPT | |
| SCHEMBL323076 | 0.81 | ALDH1A1 (0.37) | KDM4EALDH1A1TDP1KIF11MAPT | |
| SCHEMBL21834482 | 0.76 | KIF11 (0.42) | KDM4EALDH1A1TDP1KIF11MAPT | |
| SCHEMBL28511042 | 0.76 | KIF11 (0.47) | KDM4EALDH1A1TDP1KIF11MAPT | |
| SCHEMBL21811270 | 0.74 | KIF11 (0.41) | KDM4EALDH1A1TDP1KIF11MAPT | |
| SCHEMBL25279748 | 0.73 | KIF11 (0.43) | KDM4EALDH1A1TDP1KIF11MAPT | |
| SCHEMBL3146062 | 0.72 | ALDH1A1 (0.50) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL3146868 | 0.68 | KIF11 (0.46) | KDM4EALDH1A1TDP1KIF11MAPT | |
| SCHEMBL22159396 | 0.68 | ESR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902706-B2 | Process for making benzoxazines | CYTEC INDUSTRIES INC. (US) | 2018-02-27 | — | — | US | disclosed |