SCHEMBL323076

SCHEMBL323076

Nc1ccc(C(F)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
KIF11 P52732 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
PDE2A O00408 1/20 0.31
GLA P06280 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28511042 0.94 KIF11 (0.47) ALDH1A1TDP1KIF11KDM4EMEN1
SCHEMBL3146062 0.89 ALDH1A1 (0.50) ALDH1A1TDP1MEN1MAPTKMT2A
SCHEMBL22159396 0.88 ESR1 (0.38) ESR1ESR2PDE2A
SCHEMBL8496183 0.87 KDM4E (0.34) ALDH1A1TDP1KIF11KDM4EMEN1
SCHEMBL28836071 0.85 KDM4E (0.33) ALDH1A1TDP1KIF11KDM4EMEN1
SCHEMBL19901307 0.81 KDM4E (0.33) ALDH1A1TDP1KIF11KDM4EMEN1
SCHEMBL10578908 0.79 IDO1 (0.38) KDM4EESR1ESR2TSHR
SCHEMBL6516945 0.77 CYP2A6 (0.36) ESR1ESR2
SCHEMBL320072 0.77 ESR1 (0.54) ALDH1A1TDP1KIF11KDM4EMEN1
SCHEMBL3130888 0.77 TSHR (0.48) ALDH1A1TDP1MAPTESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1589 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115723393-B Support body and application thereof 杭州福斯特应用材料股份有限公司 2024-07-16 CN claimed
CN-118344581-A Preparation method of fluorine-rich polyaramid polymer membrane material 南京大学 2024-07-16 CN claimed
CN-118335989-A Positive electrode binder composition and positive electrode 深圳好电科技有限公司 2024-07-12 CN claimed
CN-118290794-A Coating type modified polyimide film with carrier film and preparation method thereof 昆山雅森电子材料科技有限公司 2024-07-05 CN claimed
CN-118271901-A Alcohol-soluble environment-friendly printing ink and preparation method thereof 厦门欧化实业有限公司 2024-07-02 CN claimed
CN-118221936-A High-performance preparation method and application of polyimide 中国科学院化学研究所 2024-06-21 CN claimed
CN-118184603-A Diamine monomer containing piperazine unit, polyimide acid salt separation membrane, and preparation method and application thereof 天津科技大学 2024-06-14 CN claimed
CN-118092074-A Chemical amplification type positive photosensitive polyimide coating adhesive and preparation method and application thereof 明士(北京)新材料开发有限公司 2024-05-28 CN claimed
CN-118099359-A Alloy negative electrode material, preparation method thereof, negative electrode material system, negative electrode plate and lithium ion battery 华为技术有限公司 2024-05-28 CN claimed
CN-118063913-A Composition with good molding property and difficulty in bonding metal, and preparation method and application thereof 上海芯密科技有限公司 2024-05-24 CN claimed
WO-2002062873-A9 PHOTOACTIVE POLYMER ROLIC AG (CH) 2002-10-03 WO claimed
WO-2002062873-A1 PHOTOACTIVE POLYMER ROLIC AG (CH) 2002-08-15 WO claimed
US-5780199-A A COPOLYAMIC ACID FROM TETRACARBOXYLIC ACID DIANHYDRIDE, ORGANIC DIAMINE, FLUORINATED DIAMINE, FLUORINATED TETRACARBOXYLIC ACID DIANHYDRIDE, A PHOTOINITIATOR AND SENSITIZER; EXPOSURE TO FORM IMAGES, PATTERNING, CROSSLINKING INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1998-07-14 US claimed
US-5725633-A Sulfonated polyimide gas separation membranes PRAXAIR TECHNOLOGY, INC. (US) 1998-03-10 US claimed
US-5239049-A Selected poly(dianhydrides) compounds, selected poly(amic acid) compounds, and selected poly(imide) compounds OLIN CORPORATION (US) 1993-08-24 US claimed
US-4978738-A FLUORINE-CONTAINING; THIN FILMS HOECHST CELANESE CORP. (US) 1990-12-18 US claimed
EP-0385306-A1 Intermediate molecular weight polyimides and method for their preparation and articles therefrom HOECHST CELANESE CORPORATION (US) 1990-09-05 EP claimed
EP-0385305-A1 Polyamide-imide polymers having fluorine-containing linking groups HOECHST CELANESE CORPORATION (US) 1990-09-05 EP claimed
US-4954610-A SOLVENT, HEAT, OXIDATION, AND CHEMICAL RESISTANCE HOECHST CELANESE CORP. (US) 1990-09-04 US claimed
US-4929405-A Ultrathin polyimide polymer flims and their preparation HOECHST CELANESE CORP. (US) 1990-05-29 US claimed