Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425014 | 0.80 | MEN1 (0.50) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL25057512 | 0.78 | MEN1 (0.56) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL18584315 | 0.78 | LMNA (0.81) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL23349147 | 0.76 | LMNA (0.62) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL11759786 | 0.76 | MEN1 (0.50) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL20978400 | 0.75 | LMNA (0.45) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL11700396 | 0.75 | LMNA (0.61) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL13061540 | 0.75 | LMNA (0.54) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL306062 | 0.75 | LMNA (0.48) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL2985725 | 0.75 | LMNA (1.00) | LMNAMEN1CYP3A4ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902985-B2 | Chemoenzymatic methods for synthesizing moenomycin analogs | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-02-27 | — | — | US | disclosed |