Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2031142 | 0.89 | HRH4 (0.54) | HRH4MEN1KMT2ASLC6A4ATM | |
| SCHEMBL1990553 | 0.86 | ADRA1A (0.45) | HRH4ADRA1AADRA1BHTR6EZH2 | |
| SCHEMBL1991149 | 0.79 | HRH4 (0.46) | HRH4MEN1KMT2AHTR6 | |
| SCHEMBL1996128 | 0.78 | HRH4 (0.46) | HRH4HTR6 | |
| SCHEMBL1994327 | 0.78 | HRH4 (0.54) | HRH4MEN1KMT2ASLC6A4ATM | |
| SCHEMBL1991700 | 0.76 | HRH4 (0.71) | HRH4MEN1KMT2A | |
| SCHEMBL1991125 | 0.76 | HRH4 (0.55) | HRH4MEN1KMT2ASLC6A4ATM | |
| SCHEMBL1996197 | 0.76 | HRH4 (0.45) | HRH4MEN1KMT2ASLC6A4 | |
| SCHEMBL1993141 | 0.76 | HRH4 (0.56) | HRH4MEN1KMT2AATM | |
| SCHEMBL1996973 | 0.75 | HRH4 (0.48) | HRH4MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | HRH4 249/4885MEN1 427/4885KMT2A 3648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.