Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2001802 | 0.84 | HRH4 (0.50) | HRH4HTR6HTR3AKDM4EALDH1A1 | |
| SCHEMBL2031142 | 0.82 | HRH4 (0.54) | HRH4MEN1KMT2AHTR3AALDH1A1 | |
| SCHEMBL1990169 | 0.79 | HRH4 (0.47) | HRH4MEN1KMT2AHTR6 | |
| SCHEMBL1996973 | 0.79 | HRH4 (0.48) | HRH4MEN1KMT2AALDH1A1 | |
| SCHEMBL1993141 | 0.77 | HRH4 (0.56) | HRH4MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1996197 | 0.77 | HRH4 (0.45) | HRH4MEN1KMT2AKDM4E | |
| SCHEMBL1989725 | 0.77 | ALDH1A1 (0.46) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL1991700 | 0.76 | HRH4 (0.71) | HRH4MEN1KMT2AHTR3AKDM4E | |
| SCHEMBL1991125 | 0.76 | HRH4 (0.55) | HRH4MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1994327 | 0.75 | HRH4 (0.54) | HRH4MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | HRH4 249/4885MEN1 427/4885KMT2A 3648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.