Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.45 |
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990169 | 0.86 | HRH4 (0.47) | ADRA1AADRA1BHTR6HRH4EZH2 | |
| SCHEMBL1994195 | 0.85 | HRH4 (0.57) | HTR6HRH4HTR3AHTR1ADRD2 | |
| SCHEMBL1993565 | 0.84 | HRH4 (0.46) | HTR6HRH4HTR3AHTR1ADRD2 | |
| SCHEMBL1993681 | 0.79 | HRH4 (0.61) | HRH4HTR3AALDH1A1 | |
| SCHEMBL2001802 | 0.76 | HRH4 (0.50) | HTR6HRH4HTR3AHTR1ADRD2 | |
| SCHEMBL1996128 | 0.76 | HRH4 (0.46) | HTR6HRH4HTR3AALDH1A1 | |
| SCHEMBL1998966 | 0.76 | EHMT1 (0.51) | HTR6HRH4HTR3AALDH1A1POLB | |
| SCHEMBL1995864 | 0.75 | PIK3R1 (0.43) | HTR6HRH4HTR3AALDH1A1 | |
| SCHEMBL1994914 | 0.74 | HRH4 (0.46) | HTR6HRH4HTR3AALDH1A1 | |
| SCHEMBL2031142 | 0.74 | HRH4 (0.54) | HRH4HTR3AHTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | ADRA1A 272/4885ADRA1B 206/4885HTR6 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.