Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.53 |
| ▸ | CTSS | P25774 | 7/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | REN | P00797 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19033721 | 0.88 | CTSK (0.54) | CTSKCTSSCA2PPARAPPARG | |
| SCHEMBL2075220 | 0.87 | REN (0.53) | CTSKCTSSPPARAPPARGREN | |
| SCHEMBL2730114 | 0.87 | REN (0.53) | CTSKCTSSPPARAPPARGREN | |
| SCHEMBL2728071 | 0.87 | REN (0.53) | CTSKCTSSPPARAPPARGREN | |
| SCHEMBL6802106 | 0.87 | CTSK (0.68) | CTSKCTSSPPARAPPARGREN | |
| SCHEMBL16384170 | 0.85 | PPARA (0.54) | CTSKCTSSCA2PPARAPPARG | |
| SCHEMBL5447774 | 0.84 | CTSK (0.52) | CTSKCTSS | |
| SCHEMBL16945658 | 0.84 | CTSK (0.52) | CTSKCTSS | |
| SCHEMBL10077582 | 0.80 | CTSS (0.53) | CTSKCTSSPPARAPPARGPPARD | |
| SCHEMBL15802560 | 0.80 | PTPN1 (0.47) | CTSKCTSSCA2PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902688-B2 | Benzamides and nicotinamides as Syk modulators | PORTOLA PHARMACEUTICALS, INC. (US) | 2018-02-27 | — | — | US | disclosed |