Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | STK17B | O94768 | 1/20 | 0.37 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | LATS1 | O95835 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17454460 | 0.86 | L3MBTL1 (0.41) | MALT1L3MBTL1ALDH1A1GFERMEN1 | |
| SCHEMBL18764806 | 0.86 | L3MBTL1 (0.55) | MALT1L3MBTL1ALDH1A1GFERMEN1 | |
| SCHEMBL18764807 | 0.85 | DRD2 (0.41) | MALT1L3MBTL1ALDH1A1GFERMEN1 | |
| SCHEMBL19902326 | 0.84 | L3MBTL1 (0.43) | MALT1L3MBTL1ALDH1A1GFERMEN1 | |
| SCHEMBL13975927 | 0.84 | MALT1 (0.43) | MALT1ALDH1A1GFERMEN1GAA | |
| SCHEMBL13740008 | 0.82 | ALDH1A1 (0.41) | MALT1ALDH1A1GFERMEN1GAA | |
| SCHEMBL13975444 | 0.81 | LMNA (0.47) | MALT1ALDH1A1GFERMEN1GAA | |
| SCHEMBL24613337 | 0.80 | KMT2A (0.43) | MALT1ALDH1A1GFERMEN1GAA | |
| SCHEMBL16899828 | 0.80 | ALDH1A1 (0.41) | MALT1ALDH1A1GFERMEN1GAA | |
| SCHEMBL19558618 | 0.80 | ALDH1A1 (0.41) | MALT1ALDH1A1GFERMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902702-B2 | Spirocycloheptanes as inhibitors of rock | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-02-27 | — | — | US | disclosed |