SCHEMBL19903549

SCHEMBL19903549

N#Cc1c(-n2c3ccc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)cc3c3cc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)ccc32)cc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1-n1c2ccc(-c3ccc(C(F)(F)F)cc3C(F)(F)F)cc2c2cc(-c3ccc(C(F)(F)F)cc3C(F)(F)F)ccc21

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 2/20 0.37
FEN1 P39748 2/20 0.37
AR P10275 5/20 0.34
CYP2C9 P11712 1/20 0.33
SCN9A Q15858 1/20 0.33
RXRA P19793 1/20 0.32
RXRG P48443 1/20 0.32
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32
ICMT O60725 2/20 0.32
KIF11 P52732 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
NAAA Q02083 1/20 0.31
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20111565 0.97 ALOX5AP (0.34) ALOX5APFEN1ARCYP2C9SCN9A
SCHEMBL19903560 0.95 AR (0.36) ALOX5APFEN1ARCYP2C9SCN9A
SCHEMBL20617059 0.95 RXRA (0.39) ALOX5APFEN1ARCYP2C9SCN9A
SCHEMBL21258835 0.94 ALOX5AP (0.39) ALOX5APFEN1ARCYP2C9SCN9A
SCHEMBL20111560 0.92 KIF11 (0.34) ALOX5APFEN1ARCYP2C9SCN9A
SCHEMBL21414281 0.91 ALOX5AP (0.36) ALOX5APFEN1ARCYP2C9SCN9A
SCHEMBL20617435 0.90 RXRA (0.36) ALOX5APFEN1ARCYP2C9SCN9A
SCHEMBL21258836 0.90 ALOX5AP (0.36) ALOX5APFEN1ARCYP2C9SCN9A
SCHEMBL19909372 0.89 KIF11 (0.39) ALOX5APFEN1ARCYP2C9SCN9A
SCHEMBL20111566 0.89 AR (0.38) ALOX5APFEN1ARCYP2C9SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10439151-B2 Organic molecules, especially for use in organic optoelectronic devices CYNORA GMBH (DE) 2019-10-08 US disclosed
EP-3360945-B1 ORGANIC ELECTROLUMINESCENT DEVICE CYNORA GMBH (DE) 2019-04-24 EP disclosed
EP-3287450-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-03-20 EP disclosed
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287450-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10439151-B2 Organic molecules, especially for use in organic optoelectronic devices OR10J3, ORC3, AOC3 ALOX5AP 3371/4885FEN1 1443/4885AR 4190/4885
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, ORC3, AOC3 ALOX5AP 3376/4885FEN1 1603/4885AR 4212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.