SCHEMBL19909372

SCHEMBL19909372

N#Cc1c(-n2c3ccc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)cc3c3cc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)ccc32)cc(-c2ccncc2)cc1-n1c2ccc(-c3ccc(C(F)(F)F)cc3C(F)(F)F)cc2c2cc(-c3ccc(C(F)(F)F)cc3C(F)(F)F)ccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.39
ALOX5AP P20292 2/20 0.37
FEN1 P39748 2/20 0.37
PDE10A Q9Y233 1/20 0.33
CYP2C9 P11712 1/20 0.33
SCN9A Q15858 1/20 0.33
S1PR1 P21453 1/20 0.33
S1PR3 Q99500 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
AR P10275 1/20 0.32
MAPK14 Q16539 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ROCK2 O75116 1/20 0.31
ROCK1 Q13464 1/20 0.31
PDE3B Q13370 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909453 0.95 PDE10A (0.36) KIF11ALOX5APFEN1PDE10ACYP2C9
SCHEMBL19919605 0.92 KIF11 (0.39) KIF11ALOX5APFEN1PDE10ACYP2C9
SCHEMBL21258835 0.90 ALOX5AP (0.39) KIF11ALOX5APFEN1CYP2C9SCN9A
SCHEMBL19913196 0.90 KIF11 (0.33) KIF11ALOX5APFEN1CYP2C9SCN9A
SCHEMBL19903549 0.89 ALOX5AP (0.37) KIF11ALOX5APFEN1CYP2C9SCN9A
SCHEMBL19909452 0.89 PDE10A (0.36) KIF11ALOX5APFEN1PDE10ACYP2C9
SCHEMBL19913195 0.88 S1PR1 (0.34) KIF11ALOX5APFEN1PDE10ACYP2C9
SCHEMBL19909419 0.88 KIF11 (0.44) KIF11NPC1RAB9ARXFP1MAPK14
SCHEMBL21414281 0.88 ALOX5AP (0.36) KIF11ALOX5APFEN1CYP2C9SCN9A
SCHEMBL19913194 0.87 KIF11 (0.34) KIF11ALOX5APFEN1PDE10ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 KIF11 3067/4885ALOX5AP 2798/4885FEN1 2478/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 KIF11 3082/4885ALOX5AP 3906/4885FEN1 1491/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 KIF11 3067/4885ALOX5AP 2798/4885FEN1 2478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.