SCHEMBL20111565

SCHEMBL20111565

N#Cc1c(-n2c3ccc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)cc3c3cc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)ccc32)cc(-c2ccc(C(F)(F)F)cc2C(F)(F)F)cc1-n1c2ccc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)cc2c2cc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)ccc21

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 2/20 0.34
FEN1 P39748 2/20 0.34
ICMT O60725 5/20 0.33
RXRA P19793 1/20 0.32
RXRG P48443 1/20 0.32
AR P10275 1/20 0.31
KIF11 P52732 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP2C9 P11712 1/20 0.31
SCN9A Q15858 1/20 0.31
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19903549 0.97 ALOX5AP (0.37) ALOX5APFEN1ICMTRXRARXRG
SCHEMBL20111560 0.95 KIF11 (0.34) ALOX5APFEN1ICMTARKIF11
SCHEMBL21258835 0.93 ALOX5AP (0.39) ALOX5APFEN1ARKIF11ALDH1A1
SCHEMBL19903560 0.92 AR (0.36) ALOX5APFEN1ICMTARKIF11
SCHEMBL25659256 0.92 KIF11 (0.36) ICMTRXRARXRGARKIF11
SCHEMBL20617059 0.92 RXRA (0.39) ALOX5APFEN1RXRARXRGAR
SCHEMBL20112055 0.92 RXRA (0.35) ALOX5APFEN1RXRARXRGAR
SCHEMBL21258672 0.91 ALOX5AP (0.34) ALOX5APFEN1RXRARXRGAR
SCHEMBL21258836 0.91 ALOX5AP (0.36) ALOX5APFEN1ARKIF11ALDH1A1
SCHEMBL21258865 0.91 AR (0.35) ALOX5APFEN1ARALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10971688-B2 Organic molecules for use in organic optoelectronic devices CYNORA GMBH (DE) 2021-04-06 US disclosed
US-20190248741-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2019-08-15 US disclosed
EP-3360945-B1 ORGANIC ELECTROLUMINESCENT DEVICE CYNORA GMBH (DE) 2019-04-24 EP disclosed
WO-2018077492-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-05-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10971688-B2 Organic molecules for use in organic optoelectronic devices OR10J3, OR51E2, OPRM1 ALOX5AP 2592/4885FEN1 1121/4885ICMT 71/4885
US-20190248741-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, ORC3, AOC3 ALOX5AP 3253/4885FEN1 1286/4885ICMT 132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.