SCHEMBL19903568

SCHEMBL19903568

N#Cc1c(-n2c3ccc(C(F)(F)F)cc3c3cc(C(F)(F)F)ccc32)cc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1-n1c2ccc(C(F)(F)F)cc2c2cc(C(F)(F)F)ccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.35
RXRG P48443 2/20 0.35
KIF11 P52732 2/20 0.35
MAPT P10636 2/20 0.33
TSHR P16473 2/20 0.33
CTSS P25774 2/20 0.33
NAAA Q02083 1/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
HSP90AA1 P07900 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
NFKB1 P19838 1/20 0.33
CYP2C19 P33261 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
KMT2A Q03164 1/20 0.33
KCNMA1 Q12791 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
RAPGEF3 O95398 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19903533 0.94 KIF11 (0.41) RXRARXRGKIF11MAPTCTSS
SCHEMBL20617087 0.93 RXRA (0.43) RXRARXRGKIF11MAPTTSHR
SCHEMBL19903520 0.93 RAPGEF3 (0.37) RXRARXRGKIF11CTSSNAAA
SCHEMBL19903552 0.92 RXRA (0.38) RXRARXRGKIF11MAPTCTSS
SCHEMBL21414228 0.89 KIF11 (0.40) RXRARXRGKIF11MAPTTSHR
SCHEMBL19903498 0.89 KIF11 (0.40) RXRARXRGKIF11NAAAMEN1
SCHEMBL19903525 0.89 KIF11 (0.39) RXRARXRGKIF11MAPTTSHR
SCHEMBL19903673 0.88 HTT (0.39) RXRARXRGKIF11MAPTCTSS
SCHEMBL20617070 0.88 RXRA (0.40) RXRARXRGKIF11MAPTCTSS
SCHEMBL20829447 0.88 KIF11 (0.39) RXRARXRGKIF11MAPTRAPGEF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10439151-B2 Organic molecules, especially for use in organic optoelectronic devices CYNORA GMBH (DE) 2019-10-08 US disclosed
EP-3360945-B1 ORGANIC ELECTROLUMINESCENT DEVICE CYNORA GMBH (DE) 2019-04-24 EP disclosed
EP-3287450-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-03-20 EP disclosed
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287450-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10439151-B2 Organic molecules, especially for use in organic optoelectronic devices OR10J3, ORC3, AOC3 RXRA 3779/4885RXRG 3669/4885KIF11 3253/4885
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, ORC3, AOC3 RXRA 3635/4885RXRG 3474/4885KIF11 3316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.