Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 3/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | RORA | P35398 | 1/20 | 0.33 |
| ▸ | RORB | Q92753 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19903669 | 1.00 | KIF11 (0.39) | KIF11RAPGEF3RAPGEF4PPARGPPARA | |
| SCHEMBL22564574 | 0.95 | RXRA (0.38) | KIF11RAPGEF3RAPGEF4PPARGPPARA | |
| SCHEMBL19903690 | 0.94 | KIF11 (0.43) | KIF11RAPGEF3RAPGEF4PPARGPPARA | |
| SCHEMBL19903533 | 0.94 | KIF11 (0.41) | KIF11PPARGPPARAICMTAR | |
| SCHEMBL19903520 | 0.94 | RAPGEF3 (0.37) | KIF11RAPGEF3RAPGEF4PPARGICMT | |
| SCHEMBL19912393 | 0.94 | KIF11 (0.36) | KIF11RAPGEF3RAPGEF4PPARGPPARA | |
| SCHEMBL19903495 | 0.91 | KIF11 (0.39) | KIF11ALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL19903550 | 0.90 | ICMT (0.37) | KIF11ICMTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22564566 | 0.89 | KIF11 (0.41) | KIF11PPARGPPARARORCRXRA | |
| SCHEMBL20617070 | 0.89 | RXRA (0.40) | KIF11RORCALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287450-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-03-20 | — | — | EP | disclosed |