Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | CTSS | P25774 | 3/20 | 0.53 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CTSH | P09668 | 1/20 | 0.53 |
| ▸ | APLNR | P35414 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198945 | 0.94 | APLNR (0.53) | CTSLCTSSCTSKCTSHAPLNR | |
| SCHEMBL29634120 | 0.87 | CTSL (0.47) | CTSLCTSSCTSKCTSHAPLNR | |
| SCHEMBL198097 | 0.86 | APLNR (0.51) | CTSLCTSSCTSKCTSHAPLNR | |
| SCHEMBL31265397 | 0.82 | CTSL (0.57) | CTSLCTSSCTSKCTSHAPLNR | |
| SCHEMBL197800 | 0.82 | APLNR (0.49) | CTSLCTSSCTSKCTSHAPLNR | |
| SCHEMBL4804770 | 0.82 | APLNR (0.55) | CTSLCTSSCTSKCTSHAPLNR | |
| SCHEMBL4804787 | 0.82 | APLNR (0.55) | CTSLCTSSCTSKCTSHAPLNR | |
| SCHEMBL197746 | 0.82 | OPRM1 (0.54) | CTSLCTSSCTSKCTSHAPLNR | |
| SCHEMBL4303904 | 0.82 | OPRM1 (0.54) | APLNROPRM1OPRK1MC4RC5AR1 | |
| SCHEMBL1029282 | 0.81 | OPRM1 (0.52) | CTSLCTSSCTSKCTSHAPLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088890-B2 | Peptides and peptidomimetic compounds, the manufacturing thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition | FIBREX MEDICAL RESEARCH & DEVELOPMENT GMBH (AT) | 2012-01-03 | — | — | US | disclosed |