Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 6/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1989861 | 0.89 | GHSR (0.50) | GHSRCHRM2L3MBTL1ALDH1A1CCR4 | |
| SCHEMBL1991756 | 0.89 | GHSR (0.62) | GHSRL3MBTL1ALDH1A1CCR4MAPK1 | |
| SCHEMBL1990394 | 0.88 | GHSR (0.49) | GHSRCHRM2L3MBTL1ALDH1A1CCR4 | |
| SCHEMBL1991288 | 0.88 | GHSR (0.49) | GHSRCHRM2LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL1990124 | 0.87 | GHSR (0.56) | GHSRBCHEACHELMNAL3MBTL1 | |
| SCHEMBL1990054 | 0.87 | GHSR (0.54) | GHSRCHRM2L3MBTL1ALDH1A1CCR4 | |
| SCHEMBL1988077 | 0.86 | GHSR (0.55) | GHSRCHRM2L3MBTL1ALDH1A1CCR4 | |
| SCHEMBL1994337 | 0.86 | GHSR (0.57) | GHSRBCHEACHELMNAL3MBTL1 | |
| SCHEMBL1991024 | 0.85 | GHSR (0.49) | GHSRCHRM2L3MBTL1CCR4DRD1 | |
| SCHEMBL1988473 | 0.84 | GHSR (0.54) | GHSRBCHELMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152232-A1 | SULFONAMIDE COMPOUNDS AND USES THEREOF | SAUNDERS JEFFREY O | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152232-A1 | SULFONAMIDE COMPOUNDS AND USES THEREOF | GHSR, GHRHR, SSTR2 | GHSR 1/4885BCHE 1889/4885CHRM2 3419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.