Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 4/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21141405 | 0.84 | RAB9A (0.42) | THRBTHRATYMSTSHRMAPT | |
| SCHEMBL1696567 | 0.83 | THRB (0.47) | ALDH1A1THRBTHRATYMSMAPT | |
| SCHEMBL30593911 | 0.83 | L3MBTL1 (0.47) | ALDH1A1THRBTHRATYMSMAPT | |
| SCHEMBL39820 | 0.83 | L3MBTL1 (0.47) | ALDH1A1THRBTHRATYMSMAPT | |
| SCHEMBL14173224 | 0.80 | THRB (0.45) | ALDH1A1THRBTHRATYMSKDM4E | |
| SCHEMBL8899213 | 0.80 | MAPT (0.42) | ALDH1A1THRBTHRATYMSTSHR | |
| SCHEMBL18352540 | 0.80 | TSHR (0.50) | ALDH1A1TSHRMAPTKDM4ELMNA | |
| SCHEMBL17708232 | 0.80 | THRB (0.42) | ALDH1A1THRBTHRATYMSTSHR | |
| SCHEMBL27494979 | 0.79 | THRB (0.43) | PDE10AALDH1A1THRBTHRATYMS | |
| SCHEMBL27766549 | 0.79 | THRB (0.39) | ALDH1A1THRBTHRATYMSCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233944-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2019-09-04 | — | — | EP | disclosed |
| EP-2393851-B1 | COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-02-28 | — | — | EP | disclosed |
| CN-102424680-A | Viral polymerase inhibitors | BOEHRINGER INGELHEIM CA LTD | 2012-04-25 | — | — | CN | disclosed |
| CN-1558759-B | Viral polymerase inhibitors | BOEHRINGER INGELHEIM CA LTD | 2012-01-25 | — | — | CN | disclosed |