Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2150640 | 0.83 | MITF (0.39) | SMN1; SMN2DRD2DRD4DRD3KMT2A | |
| SCHEMBL445915 | 0.83 | LTA4H (0.53) | SMN1; SMN2KCNH2DRD2DRD3LTA4H | |
| SCHEMBL10889093 | 0.82 | HTR2A (0.39) | KCNH2DRD2DRD4DRD3KMT2A | |
| SCHEMBL19904703 | 0.81 | MGLL (0.40) | DRD2DRD4DRD3LTA4HNR5A1 | |
| SCHEMBL430999 | 0.79 | LTA4H (0.53) | SMN1; SMN2KCNH2DRD2DRD3LTA4H | |
| SCHEMBL2150871 | 0.79 | MITF (0.39) | SMN1; SMN2DRD2DRD4DRD3KMT2A | |
| SCHEMBL6461650 | 0.79 | NR5A1 (0.43) | SMN1; SMN2NPC1RAB9AHSD17B10DRD2 | |
| SCHEMBL8389043 | 0.79 | NR5A1 (0.43) | SMN1; SMN2NPC1RAB9AHSD17B10DRD2 | |
| SCHEMBL29033057 | 0.78 | LTA4H (0.52) | SMN1; SMN2KCNH2DRD2DRD4DRD3 | |
| SCHEMBL991869 | 0.78 | LTA4H (0.53) | SMN1; SMN2KCNH2DRD2DRD3LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024020507-A2 | ORGANOPHOSPHOROUS COMPOUNDS AND USES THEREOF | JAL THERAPEUTICS, LLC (US) | 2024-01-25 | — | — | WO | disclosed |
| EP-2097428-B1 | BUTYRYLCHOLINESTERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | MGP BIOTECHNOLOGIES INC (US) | 2018-02-28 | — | — | EP | disclosed |