Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 2/20 | 0.45 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1994327 | 0.86 | HRH4 (0.54) | EHMT1HRH4ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL1993409 | 0.85 | HRH4 (0.50) | HRH4ALDH1A1KMT2AHTR3AMAPT | |
| SCHEMBL1991112 | 0.84 | HRH4 (0.65) | HRH4ALDH1A1HTR3AKDM4E | |
| SCHEMBL1990158 | 0.84 | HRH4 (0.49) | HRH4HTR3AMCHR1MAPTKDM4E | |
| SCHEMBL1993681 | 0.82 | HRH4 (0.61) | HRH4ALDH1A1HTR3AKDM4EHTT | |
| SCHEMBL1993947 | 0.78 | PRKCB (0.45) | HRH4ALDH1A1HTR3AKDM4EHTR6 | |
| SCHEMBL1995226 | 0.76 | LATS1 (0.45) | HRH4ALDH1A1HTR3AKDM4EHTR6 | |
| SCHEMBL1990553 | 0.76 | ADRA1A (0.45) | HRH4ALDH1A1POLBSMN1; SMN2HTR3A | |
| SCHEMBL1991360 | 0.75 | HRH4 (0.51) | HRH4ALDH1A1HTR3AMCHR1MAPT | |
| SCHEMBL1995864 | 0.75 | PIK3R1 (0.43) | HRH4ALDH1A1HTR3AKDM4EHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | EHMT1 3018/4885HRH4 249/4885ALDH1A1 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.