Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.50 |
| ▸ | HTR3A | P46098 | 3/20 | 0.45 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1991149 | 0.84 | HRH4 (0.46) | HRH4HTR3AHTR6KDM4EHTT | |
| SCHEMBL1993681 | 0.82 | HRH4 (0.61) | HRH4HTR3AKDM4EHTTGLA | |
| SCHEMBL1994195 | 0.79 | HRH4 (0.57) | HRH4HTR3AHTR6KDM4EHTT | |
| SCHEMBL1993565 | 0.78 | HRH4 (0.46) | HRH4HTR3AHTR6KDM4EHTT | |
| SCHEMBL1995864 | 0.77 | PIK3R1 (0.43) | HRH4HTR3AHTR6KDM4EHTT | |
| SCHEMBL1995226 | 0.77 | LATS1 (0.45) | HRH4HTR3AHTR6KDM4EHTT | |
| SCHEMBL1990553 | 0.76 | ADRA1A (0.45) | HRH4HTR3AHTR6ALDH1A1HTR1A | |
| SCHEMBL1994137 | 0.74 | HRH4 (0.50) | HRH4HTR3AHTR6KDM4EHTT | |
| SCHEMBL1993409 | 0.74 | HRH4 (0.50) | HRH4HTR3AKDM4EHTTGLA | |
| SCHEMBL1990158 | 0.74 | HRH4 (0.49) | HRH4HTR3AHTR6KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | HRH4 249/4885HTR3A 1075/4885HTR6 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.