Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ULK1 | O75385 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906105 | 0.93 | PTGDR2 (0.42) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906211 | 0.88 | KDM4E (0.34) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906247 | 0.87 | ABL1 (0.40) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906236 | 0.84 | PTGDR2 (0.38) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19905804 | 0.84 | PTGDR2 (0.38) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19905838 | 0.83 | PTGDR2 (0.37) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906329 | 0.83 | KDM4E (0.36) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906269 | 0.83 | EIF4E (0.40) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19905901 | 0.83 | PTGDR2 (0.39) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906015 | 0.83 | PIK3CG (0.38) | PTGDR2KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |