Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRF1 | P14222 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906142 | 0.92 | PRF1 (0.37) | PRF1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL15342429 | 0.80 | PRF1 (0.37) | PRF1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL19906140 | 0.80 | KDM4E (0.36) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL15333311 | 0.76 | CYP3A4 (0.39) | PRF1 | |
| SCHEMBL15333444 | 0.76 | CYP3A4 (0.39) | PRF1 | |
| SCHEMBL19906171 | 0.76 | KDM4E (0.36) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL15342057 | 0.76 | PRF1 (0.39) | PRF1 | |
| SCHEMBL19906197 | 0.75 | PTGDR2 (0.36) | KDM4EMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL19906193 | 0.75 | CASP3 (0.33) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL19906412 | 0.74 | TP53 (0.38) | KDM4EMEN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |