Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906413 | 0.86 | MAPT (0.43) | TP53MAPTKDM4EMEN1KMT2A | |
| SCHEMBL19906108 | 0.84 | CPT1A (0.35) | TP53MAPTKDM4EMEN1KMT2A | |
| SCHEMBL19906394 | 0.84 | GRM5 (0.36) | KDM4EMEN1KMT2AALDH1A1PTGDR2 | |
| SCHEMBL19906107 | 0.83 | CPT1A (0.32) | KDM4EMEN1KMT2AALDH1A1PTGDR2 | |
| SCHEMBL19906119 | 0.82 | PTGDR2 (0.39) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL19905892 | 0.82 | PTGDR2 (0.37) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL19906142 | 0.82 | PRF1 (0.37) | KDM4EMEN1KMT2AALDH1A1PTGDR2 | |
| SCHEMBL19906137 | 0.82 | PTGDR2 (0.39) | KDM4EMEN1KMT2AALDH1A1PTGDR2 | |
| SCHEMBL19906135 | 0.82 | CHRM2 (0.35) | — | |
| SCHEMBL19905897 | 0.81 | MAPT (0.39) | MAPTKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |