Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15332942 | 0.83 | KDM4E (0.48) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL19906141 | 0.80 | PRF1 (0.37) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL19906382 | 0.73 | KDM4E (0.39) | KDM4ESMN1; SMN2LMNARAB9A | |
| SCHEMBL19906268 | 0.72 | EIF4E (0.38) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19905892 | 0.72 | PTGDR2 (0.37) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL19906119 | 0.72 | PTGDR2 (0.39) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL19906412 | 0.72 | TP53 (0.38) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL19906323 | 0.72 | SMN1; SMN2 (0.43) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19906169 | 0.71 | KDM4E (0.35) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL19906086 | 0.71 | KDM4E (0.39) | KDM4EMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |