Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRF1 | P14222 | 12/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | UGCG | Q16739 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906141 | 0.92 | PRF1 (0.37) | PRF1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL19906171 | 0.83 | KDM4E (0.36) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906197 | 0.82 | PTGDR2 (0.36) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906412 | 0.82 | TP53 (0.38) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906193 | 0.82 | CASP3 (0.33) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19905880 | 0.81 | KDM4E (0.38) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906107 | 0.81 | CPT1A (0.32) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19905892 | 0.81 | PTGDR2 (0.37) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906119 | 0.81 | PTGDR2 (0.39) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19905856 | 0.81 | KDM4E (0.35) | KDM4EMEN1ALDH1A1KMT2APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |