Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 4/20 | 0.38 |
| ▸ | CPT1A | P50416 | 5/20 | 0.34 |
| ▸ | CPT1B | Q92523 | 5/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19905990 | 0.95 | GRM5 (0.39) | PTGER3GRM5KDM4EMEN1ALDH1A1 | |
| SCHEMBL19905979 | 0.92 | KDM4E (0.33) | PTGER3CPT1ACPT1BPPARDGRM5 | |
| SCHEMBL19906108 | 0.89 | CPT1A (0.35) | PTGER3CPT1ACPT1BPPARDPPARG | |
| SCHEMBL19906136 | 0.89 | GRM5 (0.36) | PTGER3CPT1ACPT1BPPARDGRM5 | |
| SCHEMBL19906202 | 0.88 | PTGER3 (0.40) | PTGER3CPT1ACPT1BKDM4EMEN1 | |
| SCHEMBL19905938 | 0.88 | PTGDR2 (0.34) | CPT1ACPT1BPPARDPPARGPPARA | |
| SCHEMBL19906195 | 0.87 | CASP3 (0.37) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906394 | 0.85 | GRM5 (0.36) | PTGER3CPT1ACPT1BPPARDGRM5 | |
| SCHEMBL19906022 | 0.84 | PTGER3 (0.37) | PTGER3CPT1ACPT1BPPARDPPARA | |
| SCHEMBL15342615 | 0.83 | CYP3A4 (0.37) | PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |