Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.63 |
| ▸ | ALPG | P10696 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19908607 | 0.81 | ALPL (0.52) | ALPLALPGMAOBALDH1A1GLA | |
| SCHEMBL19908699 | 0.79 | ALPL (0.50) | ALPLALPGMAOBALDH1A1GLA | |
| SCHEMBL3122205 | 0.79 | ALPL (0.50) | ALPLALPGMAOBALDH1A1GLA | |
| SCHEMBL23469195 | 0.78 | ALPL (0.52) | ALPLALPGMAOBALDH1A1GLA | |
| SCHEMBL11551316 | 0.76 | ALPL (0.61) | ALPLALPGMAOBALDH1A1GLA | |
| SCHEMBL11680119 | 0.76 | ALPL (0.61) | ALPLALPGMAOBALDH1A1GLA | |
| SCHEMBL11678584 | 0.76 | KDM4E (0.62) | ALPLALPGMAOBALDH1A1GLA | |
| Bromide SCHEMBL9787677 | 0.76 | ALDH1A1 (0.69) | ALPLALPGMAOBALDH1A1GLA | |
| SCHEMBL26922539 | 0.75 | ALDH1A1 (0.68) | ALPLALPGMAOBALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL11678840 | 0.75 | ALPL (0.64) | ALPLALPGMAOBALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287441-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-28 | — | — | EP | disclosed |