Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19908620 | 0.79 | ALPL (0.63) | ALPLALPGALDH1A1GLAMAOB | |
| SCHEMBL2896486 | 0.78 | ALDH1A1 (0.62) | ALDH1A1GLAHSD17B10KDM4EHPGD | |
| SCHEMBL6677112 | 0.78 | ALDH1A1 (0.49) | ALDH1A1GLAMAOBHSD17B10KDM4E | |
| SCHEMBL5191523 | 0.77 | ALDH1A1 (0.56) | ALDH1A1GLAHSD17B10KDM4EHPGD | |
| SCHEMBL10597819 | 0.76 | ALDH1A1 (0.58) | ALDH1A1GLAHSD17B10KDM4EHPGD | |
| SCHEMBL559271 | 0.76 | ALDH1A1 (0.58) | ALDH1A1GLAHSD17B10KDM4EHPGD | |
| SCHEMBL15642553 | 0.74 | HRH3 (0.63) | ALPLALPGALDH1A1GLAHSD17B10 | |
| SCHEMBL11384521 | 0.74 | ALDH1A1 (0.50) | ALDH1A1GLAHSD17B10KDM4EHPGD | |
| SCHEMBL11807447 | 0.73 | ALDH1A1 (0.56) | ALPLALPGALDH1A1GLAMAOB | |
| SCHEMBL15642605 | 0.73 | HRH3 (0.65) | ALDH1A1GLAHSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013126205-A1 | MIXED MONOAMINE REUPTAKE INHIBITOR IN A BIODEGRADABLE POLYMER CARRIER | WARSAW ORTHOPEDIC, INC. (US) | 2013-08-29 | — | — | WO | claimed |
| US-20130217673-A1 | MIXED MONOAMINE REUPTAKE INHIBITOR IN A BIODEGRADABLE POLYMER CARRIER | WARSAW ORTHOPEDIC, INC (US) | 2013-08-22 | — | — | US | claimed |
| US-6929805-B2 | For oral administration comprising an analgesic with rapid onset of action and at least one systemically acting analgesic with sustained action, such as a combination of benzocaine and acetylsalicylic acid (ASA) | BAYER AKTIENGESELLSCHAFT (DE) | 2005-08-16 | — | — | US | claimed |
| US-5811547-A | Method for inducing crystalline state transition in medicinal substance | NIPPON SHINYAJU CO., LTD. (JP) | 1998-09-22 | — | — | US | claimed |
| WO-2013126205-A1 | MIXED MONOAMINE REUPTAKE INHIBITOR IN A BIODEGRADABLE POLYMER CARRIER | WARSAW ORTHOPEDIC, INC. (US) | 2013-08-29 | — | — | WO | disclosed |
| US-20130217673-A1 | MIXED MONOAMINE REUPTAKE INHIBITOR IN A BIODEGRADABLE POLYMER CARRIER | WARSAW ORTHOPEDIC, INC (US) | 2013-08-22 | — | — | US | disclosed |
| US-20100022439-A1 | Nanostructures with High Load of Active Agents | PURDUE PHARMA L.P. (US) | 2010-01-28 | — | — | US | disclosed |
| US-6929805-B2 | For oral administration comprising an analgesic with rapid onset of action and at least one systemically acting analgesic with sustained action, such as a combination of benzocaine and acetylsalicylic acid (ASA) | BAYER AKTIENGESELLSCHAFT (DE) | 2005-08-16 | — | — | US | disclosed |
| EP-0979087-B1 | ANALGESIC COMBINATION | BAYER AG (DE) | 2003-11-12 | — | — | EP | disclosed |
| US-20010002999-A1 | ANALGESIC COMBINATION | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2001-06-07 | — | — | US | disclosed |
| EP-0979087-A1 | ANALGESIC COMBINATION | BAYER AG (DE) | 2000-02-16 | — | — | EP | disclosed |
| EP-0665009-B1 | CRYSTALLINE CONDITION DISLOCATING METHOD | NIPPON SHINYAKU CO LTD (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998046235-A1 | ANALGESIC COMBINATION | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-22 | — | — | WO | disclosed |
| US-5811547-A | Method for inducing crystalline state transition in medicinal substance | NIPPON SHINYAJU CO., LTD. (JP) | 1998-09-22 | — | — | US | disclosed |
| EP-0665009-A1 | CRYSTALLINE CONDITION DISLOCATING METHOD | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1995-08-02 | — | — | EP | disclosed |