Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PLEC | Q15149 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19908699 | 0.90 | ALPL (0.50) | ALPLALPGALDH1A1GLAMAOB | |
| SCHEMBL19908620 | 0.81 | ALPL (0.63) | ALPLALPGALDH1A1GLAMAOB | |
| SCHEMBL22788205 | 0.75 | KDM4E (0.41) | ALDH1A1KDM4EHPGDHTTGFER | |
| SCHEMBL3063269 | 0.74 | KDM4E (0.57) | ALDH1A1KDM4EHPGDHTTGFER | |
| SCHEMBL23469195 | 0.74 | ALPL (0.52) | ALPLALPGALDH1A1GLAMAOB | |
| SCHEMBL3122205 | 0.72 | ALPL (0.50) | ALPLALPGALDH1A1GLAMAOB | |
| SCHEMBL2014323 | 0.72 | LNPEP (0.56) | ALDH1A1GLAKDM4EHPGDHTT | |
| SCHEMBL3416308 | 0.71 | ALDH1A1 (0.54) | ALDH1A1GLAKDM4EHPGDMAPT | |
| SCHEMBL3355586 | 0.71 | PTGER4 (0.53) | ALDH1A1GLAKDM4EMAPTGAA | |
| SCHEMBL13497806 | 0.70 | PTGER4 (0.58) | ALDH1A1KDM4EHPGDHTTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287441-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-28 | — | — | EP | disclosed |