SCHEMBL19908905

SCHEMBL19908905

N#Cc1ccc(-c2ccc3c(c2)c2cc(-c4ccc(C#N)cc4)ccc2n3-c2cc(-c3ccncc3)cc(-n3c4ccc(-c5ccc(C#N)cc5)cc4c4cc(-c5ccc(C#N)cc5)ccc43)c2C#N)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 2/20 0.37
MAP4K4 O95819 1/20 0.37
CYP11B2 P19099 2/20 0.37
MAPK14 Q16539 3/20 0.37
CSNK1A1 P48729 1/20 0.37
CSNK1D P48730 1/20 0.37
PGR P06401 1/20 0.36
LRRK2 Q5S007 1/20 0.36
GCGR P47871 1/20 0.36
CYP11B1 P15538 1/20 0.35
GSK3A P49840 1/20 0.35
GSK3B P49841 1/20 0.35
PKN1 Q16512 1/20 0.34
PKN2 Q16513 1/20 0.34
MAPKAPK2 P49137 2/20 0.34
CYP19A1 P11511 1/20 0.34
MAPK13 O15264 1/20 0.34
RAF1 P04049 1/20 0.34
MAPK12 P53778 1/20 0.34
MAPK11 Q15759 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19919542 0.94 PTGER4 (0.38) FLT3MAP4K4CYP11B2MAPK14CSNK1A1
SCHEMBL19909485 0.94 FLT3 (0.34) FLT3MAP4K4MAPK14CSNK1A1CSNK1D
SCHEMBL19909122 0.92 PKN1 (0.38) FLT3CYP11B2MAPK14CSNK1A1CSNK1D
SCHEMBL19909504 0.90 AURKA (0.43) MAP4K4GSK3AGSK3B
SCHEMBL19909016 0.90 ADORA1 (0.42) CYP11B2LRRK2GSK3AGSK3B
SCHEMBL19908908 0.90 FLT3 (0.40) FLT3MAP4K4CYP11B2MAPK14CSNK1A1
SCHEMBL19909062 0.88 PIK3CD (0.39) FLT3GSK3BMAPKAPK2PDE10AKDR
SCHEMBL19908962 0.88 MAPK14 (0.34) FLT3CYP11B2MAPK14LRRK2GSK3A
SCHEMBL21414180 0.88 MAP4K4 (0.37) MAP4K4PGRMAPKAPK2CYP19A1
SCHEMBL19909064 0.87 NR4A2 (0.34) MAPK14GSK3BPDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 FLT3 2571/4885MAP4K4 3439/4885CYP11B2 402/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 FLT3 3269/4885MAP4K4 3359/4885CYP11B2 965/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 FLT3 2571/4885MAP4K4 3439/4885CYP11B2 402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.