SCHEMBL19909485

SCHEMBL19909485

N#Cc1cc(C#N)cc(-c2ccc3c(c2)c2cc(-c4cc(C#N)cc(C#N)c4)ccc2n3-c2cc(-c3ccncc3)cc(-n3c4ccc(-c5cc(C#N)cc(C#N)c5)cc4c4cc(-c5cc(C#N)cc(C#N)c5)ccc43)c2C#N)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 2/20 0.34
CSNK1A1 P48729 1/20 0.34
CSNK1D P48730 1/20 0.34
MAPK14 Q16539 1/20 0.34
CYP19A1 P11511 3/20 0.33
GSK3B P49841 2/20 0.33
AURKA O14965 1/20 0.33
GSK3A P49840 1/20 0.33
PDE10A Q9Y233 1/20 0.33
MAP4K4 O95819 1/20 0.33
NR4A2 P43354 1/20 0.33
CCNC P24863 1/20 0.33
CDK8 P49336 1/20 0.33
ROCK2 O75116 1/20 0.32
ROCK1 Q13464 1/20 0.32
AAK1 Q2M2I8 4/20 0.32
CHEK1 O14757 1/20 0.32
MKNK1 Q9BUB5 1/20 0.32
BMP2K Q9NSY1 1/20 0.32
GRM5 P41594 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19908962 0.94 MAPK14 (0.34) FLT3MAPK14CYP19A1GSK3BAURKA
SCHEMBL19908905 0.94 FLT3 (0.37) FLT3CSNK1A1CSNK1DMAPK14CYP19A1
SCHEMBL19909504 0.91 AURKA (0.43) GSK3BAURKAGSK3AMAP4K4ROCK2
SCHEMBL21414247 0.91 MAP4K4 (0.35) MAP4K4
SCHEMBL19908963 0.90 FLT3 (0.37) FLT3CYP19A1GSK3BAURKAGSK3A
SCHEMBL21414180 0.89 MAP4K4 (0.37) CYP19A1MAP4K4CHEK1
SCHEMBL19909016 0.88 ADORA1 (0.42) GSK3BGSK3ACDK8ROCK1MKNK1
SCHEMBL19909122 0.88 PKN1 (0.38) FLT3CSNK1A1CSNK1DMAPK14CYP19A1
SCHEMBL19919542 0.88 PTGER4 (0.38) FLT3CSNK1A1CSNK1DMAPK14GSK3B
SCHEMBL19909505 0.87 AURKA (0.40) FLT3GSK3BAURKAGSK3AMAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 FLT3 2571/4885CSNK1A1 4231/4885CSNK1D 3662/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 FLT3 3269/4885CSNK1A1 2962/4885CSNK1D 1514/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 FLT3 2571/4885CSNK1A1 4231/4885CSNK1D 3662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.