Sugi Predict

Sugi Predict / Compounds / SCHEMBL19908944

SCHEMBL19908944

SCHEMBL19908944

Cc1cc(C)cc(-c2ccc3c4ccccc4n(-c4cc(C#N)cc(-n5c6ccccc6c6ccc(-c7cc(C)cc(C)c7)cc65)c4-c4ccncc4)c3c2)c1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MAPK14 Q16539 5/20 0.41
▸ GRM5 P41594 3/20 0.38
▸ FLT3 P36888 2/20 0.36
▸ PDE9A O76083 1/20 0.33
▸ PDE1C Q14123 1/20 0.33
▸ CHEK1 O14757 2/20 0.33
▸ ABCG2 Q9UNQ0 1/20 0.32
▸ CSNK1A1 P48729 1/20 0.32
▸ CSNK1D P48730 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ PTGER4 P35408 1/20 0.32
▸ TNKS2 Q9H2K2 1/20 0.32
▸ IMPDH2 P12268 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19908940 0.94 GRM5 (0.39) MAPK14GRM5FLT3CHEK1CSNK1A1
SCHEMBL19908941 0.94 MAPK14 (0.41) MAPK14GRM5FLT3PDE9APDE1C
SCHEMBL19913160 0.93 MAPK14 (0.42) MAPK14GRM5FLT3ALDH1A1
SCHEMBL19908939 0.93 MAPK14 (0.40) MAPK14GRM5FLT3PDE9APDE1C
SCHEMBL19909117 0.91 MAPK14 (0.39) MAPK14GRM5FLT3ABCG2CSNK1A1
SCHEMBL19908961 0.91 MAPK14 (0.36) MAPK14GRM5FLT3PDE9APDE1C
SCHEMBL19913166 0.91 MAPK14 (0.37) MAPK14GRM5FLT3
SCHEMBL19913140 0.89 MAPK14 (0.37) MAPK14GRM5FLT3PDE9APDE1C
SCHEMBL19909478 0.89 FLT3 (0.41) MAPK14FLT3CHEK1CSNK1A1CSNK1D
SCHEMBL19913150 0.89 MAPK14 (0.39) MAPK14FLT3ABCG2IMPDH2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 — — US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 — — US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 — — US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 — — US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 — — US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 MAPK14 2544/4885GRM5 1534/4885FLT3 2571/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 MAPK14 2787/4885GRM5 4073/4885FLT3 3269/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 MAPK14 2544/4885GRM5 1534/4885FLT3 2571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.