SCHEMBL19909117

SCHEMBL19909117

N#Cc1cc(C#N)cc(-c2ccc3c4ccccc4n(-c4cc(C#N)cc(-n5c6ccccc6c6ccc(-c7cc(C#N)cc(C#N)c7)cc65)c4-c4ccncc4)c3c2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 5/20 0.39
FLT3 P36888 2/20 0.36
CSNK1A1 P48729 1/20 0.34
CSNK1D P48730 1/20 0.34
PGR P06401 1/20 0.34
SLC6A2 P23975 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.32
USP2 O75604 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
CASP1 P29466 1/20 0.32
GRM5 P41594 2/20 0.32
PTGER4 P35408 1/20 0.32
AURKA O14965 1/20 0.31
GSK3A P49840 1/20 0.31
GSK3B P49841 1/20 0.31
BRAF P15056 1/20 0.31
KDR P35968 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909119 0.94 FLT3 (0.37) MAPK14FLT3CSNK1A1CSNK1DPGR
SCHEMBL19909164 0.93 USP2 (0.40) MAPK14FLT3ABCG2USP2CYP1A2
SCHEMBL19909114 0.93 MAPK14 (0.39) MAPK14FLT3CSNK1A1CSNK1DPGR
SCHEMBL19913150 0.93 MAPK14 (0.39) MAPK14FLT3ABCG2USP2CYP1A2
SCHEMBL19909478 0.93 FLT3 (0.41) MAPK14FLT3CSNK1A1CSNK1DSLC6A2
SCHEMBL19908944 0.91 MAPK14 (0.41) MAPK14FLT3CSNK1A1CSNK1DABCG2
SCHEMBL21414149 0.90 PGR (0.37) PGRGRM5PTGER4
SCHEMBL21757798 0.90 MAPK14 (0.40) MAPK14FLT3CSNK1A1CSNK1DSLC6A2
SCHEMBL19908939 0.90 MAPK14 (0.40) MAPK14FLT3HPGDGRM5
SCHEMBL19913152 0.89 IMPDH2 (0.39) MAPK14FLT3CSNK1A1CSNK1DAURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 MAPK14 2544/4885FLT3 2571/4885CSNK1A1 4231/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 MAPK14 2787/4885FLT3 3269/4885CSNK1A1 2962/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 MAPK14 2544/4885FLT3 2571/4885CSNK1A1 4231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.