SCHEMBL19908952

SCHEMBL19908952

N#Cc1ccc(-c2ccc3c(c2)c2cc(-c4ccc(C#N)cc4C#N)ccc2n3-c2cc(C#N)cc(-n3c4ccc(-c5ccc(C#N)cc5C#N)cc4c4cc(-c5ccc(C#N)cc5C#N)ccc43)c2-c2ccncc2)c(C#N)c1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 2/20 0.38
CSNK1A1 P48729 1/20 0.38
CSNK1D P48730 1/20 0.38
MAPK14 Q16539 1/20 0.38
STS P08842 1/20 0.36
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
LRRK2 Q5S007 4/20 0.35
CYP11B1 P15538 2/20 0.34
CYP11B2 P19099 2/20 0.34
CYP19A1 P11511 1/20 0.33
XDH P47989 1/20 0.33
BRAF P15056 1/20 0.33
KDR P35968 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
PKN1 Q16512 1/20 0.33
PKN2 Q16513 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909510 0.95 FLT3 (0.37) FLT3CSNK1A1CSNK1DMAPK14STS
SCHEMBL19908953 0.91 FLT3 (0.40) FLT3CSNK1A1CSNK1DMAPK14STS
SCHEMBL19909161 0.89 CYP1A2 (0.39) CSNK1A1CSNK1DMAPK14CYP19A1LMNA
SCHEMBL19909506 0.88 FLT3 (0.39) FLT3CSNK1A1CSNK1DMAPK14STS
SCHEMBL21414139 0.88 STS (0.39) STSPRMT5WDR77
SCHEMBL19919622 0.87 STS (0.39) FLT3CSNK1A1CSNK1DMAPK14STS
SCHEMBL19908950 0.87 CSNK1A1 (0.41) FLT3CSNK1A1CSNK1DMAPK14LRRK2
SCHEMBL21931766 0.86 PRMT5 (0.41) STSPRMT5WDR77CYP11B1CYP11B2
SCHEMBL21546784 0.86 STS (0.38) STSPRMT5WDR77
SCHEMBL19908924 0.86 CYP1A2 (0.37) FLT3MAPK14LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 FLT3 2571/4885CSNK1A1 4231/4885CSNK1D 3662/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 FLT3 3269/4885CSNK1A1 2962/4885CSNK1D 1514/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 FLT3 2571/4885CSNK1A1 4231/4885CSNK1D 3662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.