SCHEMBL19909510

SCHEMBL19909510

N#Cc1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cc(C#N)cc(-n3c4ccccc4c4cc(-c5ccc(C#N)cc5C#N)ccc43)c2-c2ccncc2)c(C#N)c1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 2/20 0.37
STS P08842 1/20 0.35
MAPK14 Q16539 3/20 0.35
CYP11B1 P15538 2/20 0.35
CYP11B2 P19099 2/20 0.35
CYP19A1 P11511 1/20 0.35
CSNK1A1 P48729 1/20 0.35
CSNK1D P48730 1/20 0.35
PTGER4 P35408 1/20 0.35
LRRK2 Q5S007 4/20 0.34
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19908952 0.95 FLT3 (0.38) FLT3STSMAPK14CYP11B1CYP11B2
SCHEMBL19909506 0.94 FLT3 (0.39) FLT3STSMAPK14CYP11B1CYP11B2
SCHEMBL19908924 0.92 CYP1A2 (0.37) FLT3MAPK14
SCHEMBL19919713 0.90 FLT3 (0.35) FLT3MAPK14CYP11B1CYP11B2CYP19A1
SCHEMBL21414263 0.89 STS (0.38) STSPTGER4PRMT5WDR77
SCHEMBL19909006 0.89 STS (0.38) FLT3STSCYP11B1CYP11B2CYP19A1
SCHEMBL21546671 0.89 STS (0.37) STSPTGER4
SCHEMBL19908953 0.88 FLT3 (0.40) FLT3STSMAPK14CYP11B1CYP11B2
SCHEMBL19909161 0.88 CYP1A2 (0.39) MAPK14CYP19A1CSNK1A1CSNK1D
SCHEMBL19909037 0.88 MAPK14 (0.38) FLT3MAPK14CYP11B1CYP11B2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 FLT3 2571/4885STS 2528/4885MAPK14 2544/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 FLT3 3269/4885STS 2306/4885MAPK14 2787/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 FLT3 2571/4885STS 2528/4885MAPK14 2544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.