SCHEMBL19909129

SCHEMBL19909129

Cc1cc(-c2c(-n3c4ccccc4c4ccc(-c5ccc(C#N)cc5C#N)cc43)cc(C#N)cc2-n2c3ccccc3c3ccc(-c4ccc(C#N)cc4C#N)cc32)cc(C)n1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
STS P08842 1/20 0.34
PTGER4 P35408 1/20 0.34
FFAR4 Q5NUL3 1/20 0.33
GABRA1 P14867 2/20 0.32
GABRG2 P18507 2/20 0.32
GABRB3 P28472 2/20 0.32
GABRA2 P47869 2/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
XDH P47989 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
PRMT5 O14744 1/20 0.31
WDR77 Q9BQA1 1/20 0.31
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909393 0.95 STS (0.35) STSFFAR4GABRA1GABRG2GABRB3
SCHEMBL19909009 0.92 GABRA1 (0.39) GABRA1GABRG2GABRB3GABRA2GABRA5
SCHEMBL22563559 0.91 PTGER4 (0.35) STSPTGER4FFAR4GABRA1GABRG2
SCHEMBL19909319 0.90 STS (0.35) STSPTGER4FFAR4GABRA1GABRG2
SCHEMBL21414258 0.90 STS (0.38) STSFFAR4PRMT5WDR77
SCHEMBL19919756 0.89 STS (0.35) STSPTGER4FFAR4GABRA1GABRG2
SCHEMBL19919729 0.89 GABRA1 (0.41) GABRA1GABRG2GABRB3GABRA2GABRA5
SCHEMBL21278794 0.89 STS (0.32) STSPTGER4FFAR4GABRA1GABRG2
SCHEMBL19909545 0.89 PTGER4 (0.36) PTGER4MEN1KMT2AATMCYP11B1
SCHEMBL19909200 0.88 STS (0.34) STSPTGER4FFAR4GABRA1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 STS 2528/4885PTGER4 1123/4885FFAR4 3809/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 STS 2306/4885PTGER4 1386/4885FFAR4 3769/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 STS 2528/4885PTGER4 1123/4885FFAR4 3809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.