Sugi Predict

Sugi Predict / Compounds / SCHEMBL19909131

SCHEMBL19909131

SCHEMBL19909131

N#Cc1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cc(C#N)cc(-n3c4ccccc4c4cc(-c5ccc(C#N)cc5C#N)ccc43)c2-c2cc(-c3ccccc3)nc(-c3ccccc3)c2)c(C#N)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MYC P01106 1/20 0.37
▸ PTGER4 P35408 1/20 0.35
▸ ABCG2 Q9UNQ0 2/20 0.35
▸ ABCB1 P08183 1/20 0.35
▸ GABRG2 P18507 2/20 0.34
▸ GABRB3 P28472 2/20 0.34
▸ GABRA5 P31644 2/20 0.34
▸ GABRA3 P34903 2/20 0.34
▸ GABRA1 P14867 1/20 0.34
▸ STS P08842 1/20 0.34
▸ CSNK2A1 P68400 2/20 0.33
▸ JAK2 O60674 1/20 0.33
▸ PRKD3 O94806 1/20 0.33
▸ ABL1 P00519 1/20 0.33
▸ EGFR P00533 1/20 0.33
▸ ERBB2 P04626 1/20 0.33
▸ LCK P06239 1/20 0.33
▸ CDK1 P06493 1/20 0.33
▸ CSF1R P07333 1/20 0.33
▸ LYN P07948 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909392 0.97 MYC (0.39) MYCABCG2ABCB1GABRG2GABRB3
SCHEMBL22563561 0.92 ABCG2 (0.37) MYCPTGER4ABCG2ABCB1GABRG2
SCHEMBL19919474 0.92 GABRG2 (0.41) MYCABCG2ABCB1GABRG2GABRB3
SCHEMBL22562282 0.91 PTGER4 (0.35) MYCPTGER4ABCG2ABCB1GABRG2
SCHEMBL21278792 0.91 ABCG2 (0.37) MYCPTGER4ABCG2ABCB1STS
SCHEMBL22562560 0.91 PTGER4 (0.34) MYCPTGER4ABCG2ABCB1GABRG2
SCHEMBL19909321 0.90 MYC (0.38) MYCPTGER4ABCG2ABCB1GABRG2
SCHEMBL19919754 0.89 MYC (0.38) MYCPTGER4ABCG2ABCB1GABRG2
SCHEMBL22563520 0.89 ABCG2 (0.38) MYCPTGER4ABCG2ABCB1GABRG2
SCHEMBL19913333 0.89 MYC (0.38) MYCPTGER4ABCG2ABCB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 — — US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 — — US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 — — US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 — — US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 MYC 1697/4885PTGER4 1123/4885ABCG2 624/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 MYC 1636/4885PTGER4 1386/4885ABCG2 3492/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 MYC 1697/4885PTGER4 1123/4885ABCG2 624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.