SCHEMBL19909153

SCHEMBL19909153

Cc1ccc2c3ccc(C)cc3n(-c3cc(-c4ccncc4)cc(-n4c5cc(C)ccc5c5ccc(C)cc54)c3C#N)c2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.35
LRRK2 Q5S007 2/20 0.34
CCNC P24863 1/20 0.34
CDK8 P49336 1/20 0.34
ALDH1A1 P00352 2/20 0.33
PIK3CA P42336 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
MAOA P21397 1/20 0.33
KDM4E B2RXH2 3/20 0.33
GAA P10253 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
SQOR Q9Y6N5 1/20 0.33
ABL1 P00519 1/20 0.32
LMNA P02545 3/20 0.32
MAPT P10636 2/20 0.32
PDE10A Q9Y233 2/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909152 0.94 CYP11B2 (0.38) TDP1ALDH1A1CYP11B1CYP11B2MAOA
SCHEMBL19909059 0.92 PIK3CA (0.37) TDP1ALDH1A1PIK3CALMNAMAPT
SCHEMBL19913184 0.90 KIF11 (0.38) SMN1; SMN2LMNAPDE10AHTTPIK3CD
SCHEMBL19908916 0.89 TDP1 (0.35) TDP1LRRK2CCNCCDK8ALDH1A1
SCHEMBL19909060 0.88 KDM5B (0.39) PIK3CAABL1LMNAMAPTPDE10A
SCHEMBL19909057 0.88 ABL1 (0.39) TDP1LRRK2ALDH1A1PIK3CASMN1; SMN2
SCHEMBL19913182 0.88 PIP4K2A (0.41) ALDH1A1PIK3CAKDM4EHPGDADORA1
SCHEMBL19919473 0.88 PDE9A (0.35) TDP1ALDH1A1PIK3CASMN1; SMN2CYP11B2
SCHEMBL19909426 0.88 PIP4K2A (0.42) ALDH1A1SMN1; SMN2CYP11B1CYP11B2KDM4E
SCHEMBL19913187 0.87 PDE9A (0.39) TDP1ALDH1A1PIK3CASMN1; SMN2CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed