SCHEMBL19909223

SCHEMBL19909223

Cc1ccc(-c2ccc3c4ccc(-c5ccc(C)cc5C)cc4n(-c4cc(-c5cc(C)nc(C)c5)cc(-n5c6cc(-c7ccc(C)cc7C)ccc6c6ccc(-c7ccc(C)cc7C)cc65)c4C#N)c3c2)c(C)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.35
KDM4E B2RXH2 9/20 0.34
HPGD P15428 6/20 0.34
ALDH1A1 P00352 5/20 0.34
HSD17B10 Q99714 4/20 0.34
RECQL P46063 1/20 0.34
NPSR1 Q6W5P4 3/20 0.33
PPARG P37231 2/20 0.33
RXFP1 Q9HBX9 2/20 0.33
STAT3 P40763 1/20 0.33
NR2E3 Q9Y5X4 1/20 0.33
NCOR2 Q9Y618 1/20 0.33
THRB P10828 2/20 0.32
AURKA O14965 1/20 0.32
KDR P35968 1/20 0.32
AURKB Q96GD4 1/20 0.32
METAP2 P50579 1/20 0.32
ADORA2A P29274 2/20 0.32
ADORA1 P30542 2/20 0.32
NCOA2 Q15596 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909221 0.95 PDE9A (0.34) ABL1KDM4EHPGDALDH1A1HSD17B10
SCHEMBL23487671 0.91 ABL1 (0.34) ABL1KDM4EHPGDALDH1A1HSD17B10
SCHEMBL19909130 0.88 AURKA (0.34) KDM4EHPGDALDH1A1HSD17B10RECQL
SCHEMBL19909057 0.88 ABL1 (0.39) ABL1ALDH1A1TDP1SMN1; SMN2MEN1
SCHEMBL21414172 0.87 BIRC5 (0.31) ABL1BIRC5GRM2
SCHEMBL19909435 0.87 AR (0.38) ABL1KDM4EHPGDALDH1A1HSD17B10
SCHEMBL19909222 0.87 AURKA (0.38) KDM4EHPGDALDH1A1NPSR1PPARG
SCHEMBL19942716 0.87 ABL1 (0.34) ABL1KDM4EHPGDHSD17B10NPSR1
SCHEMBL23487314 0.87 PDE9A (0.33) ABL1KDM4EHPGDALDH1A1HSD17B10
SCHEMBL22158399 0.86 BIRC5 (0.31) ABL1KDM4EBIRC5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 ABL1 2890/4885KDM4E 4526/4885HPGD 2205/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 ABL1 2221/4885KDM4E 3845/4885HPGD 836/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 ABL1 2890/4885KDM4E 4526/4885HPGD 2205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.