SCHEMBL19909057

SCHEMBL19909057

Cc1ccc(-c2ccc3c4ccc(-c5ccc(C)cc5C)cc4n(-c4cc(-c5ccncc5)cc(-n5c6cc(-c7ccc(C)cc7C)ccc6c6ccc(-c7ccc(C)cc7C)cc65)c4C#N)c3c2)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 2/20 0.39
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
FLT3 P36888 2/20 0.33
CHEK1 O14757 1/20 0.33
SLC2A1 P11166 1/20 0.33
GAA P10253 1/20 0.33
SQOR Q9Y6N5 2/20 0.32
PIK3CA P42336 1/20 0.31
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
DYRK3 O43781 1/20 0.31
ROCK2 O75116 1/20 0.31
RPS6KA5 O75582 1/20 0.31
RPS6KA4 O75676 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909055 0.95 ABL1 (0.36) ABL1TDP1MEN1NPC1RAB9A
SCHEMBL19913185 0.91 MEN1 (0.37) ABL1TDP1MEN1NPC1RAB9A
SCHEMBL19919788 0.90 ABL1 (0.33) ABL1TDP1MEN1NPC1RAB9A
SCHEMBL19909063 0.89 SQOR (0.34) ABL1TDP1MEN1NPC1RAB9A
SCHEMBL19909059 0.88 PIK3CA (0.37) TDP1FLT3CHEK1PIK3CAALDH1A1
SCHEMBL19909153 0.88 TDP1 (0.35) ABL1TDP1MEN1KMT2ACYP11B1
SCHEMBL19909418 0.88 ABL1 (0.39) ABL1TDP1CYP11B1CYP11B2CHEK1
SCHEMBL19909223 0.88 ABL1 (0.35) ABL1TDP1MEN1RAB9AKMT2A
SCHEMBL23912088 0.87 CYP11B2 (0.41) ABL1TDP1NPC1RAB9ACYP11B1
SCHEMBL21414172 0.86 BIRC5 (0.31) ABL1CYP11B1CYP11B2CHEK1BIRC5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 ABL1 2890/4885TDP1 4039/4885MEN1 3205/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 ABL1 2221/4885TDP1 3930/4885MEN1 2554/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 ABL1 2890/4885TDP1 4039/4885MEN1 3205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.