SCHEMBL19909340

SCHEMBL19909340

N#Cc1cc(-n2c3ccc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)cc3c3cc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)ccc32)c(-c2ccncc2)c(-n2c3ccc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)cc3c3cc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)ccc32)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 2/20 0.36
FEN1 P39748 2/20 0.36
KIF11 P52732 2/20 0.36
MAPK14 Q16539 2/20 0.35
CSNK1A1 P48729 1/20 0.34
CSNK1D P48730 1/20 0.34
RIPK3 Q9Y572 1/20 0.33
CYP2C9 P11712 1/20 0.32
SCN9A Q15858 1/20 0.32
S1PR1 P21453 1/20 0.32
S1PR3 Q99500 1/20 0.32
LRRK2 Q5S007 1/20 0.32
DGAT1 O75907 1/20 0.31
SOAT1 P35610 1/20 0.31
KCNH2 Q12809 1/20 0.31
AR P10275 1/20 0.31
CYP3A4 P08684 2/20 0.31
CYP3A5 P20815 2/20 0.31
FLT3 P36888 2/20 0.31
SRC P12931 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909106 0.95 S1PR1 (0.35) ALOX5APFEN1KIF11MAPK14CSNK1A1
SCHEMBL19919811 0.92 ALOX5AP (0.36) ALOX5APFEN1KIF11MAPK14CSNK1A1
SCHEMBL22170411 0.91 S1PR1 (0.35) ALOX5APFEN1KIF11MAPK14CYP2C9
SCHEMBL19913168 0.90 LRRK2 (0.32) ALOX5APFEN1KIF11MAPK14CSNK1A1
SCHEMBL21414156 0.90 ALOX5AP (0.36) ALOX5APFEN1KIF11CYP2C9SCN9A
SCHEMBL19909093 0.90 S1PR1 (0.35) ALOX5APFEN1KIF11MAPK14RIPK3
SCHEMBL21258763 0.90 ALOX5AP (0.38) ALOX5APFEN1KIF11CYP2C9SCN9A
SCHEMBL20617429 0.89 RXRA (0.38) ALOX5APFEN1KIF11CYP2C9SCN9A
SCHEMBL19903685 0.89 ALOX5AP (0.36) ALOX5APFEN1KIF11CYP2C9SCN9A
SCHEMBL19913169 0.88 S1PR1 (0.34) ALOX5APFEN1MAPK14CYP2C9SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 ALOX5AP 2798/4885FEN1 2478/4885KIF11 3067/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 ALOX5AP 3906/4885FEN1 1491/4885KIF11 3082/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 ALOX5AP 2798/4885FEN1 2478/4885KIF11 3067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.