SCHEMBL19909436

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19909437	0.96	KDM5B (0.42)	KDM5BKDM4AADORA2AADORA1ALDH1A1
	SCHEMBL19913312	0.93	KDM5B (0.39)	KDM5BKDM4AADORA2AADORA1ALDH1A1
	SCHEMBL19913302	0.92	KDM4E (0.40)	KDM5BKDM4AADORA2AADORA1ALDH1A1
	SCHEMBL22563589	0.92	KDM4A (0.39)	KDM5BKDM4AADORA2AADORA1ALDH1A1
	SCHEMBL19913313	0.91	PDE9A (0.39)	KDM5BADORA2AADORA1ALDH1A1HPGD
	SCHEMBL19919668	0.90	ADORA2A (0.38)	ADORA2AADORA1ALDH1A1HSD17B10KMT2A
	SCHEMBL19909132	0.90	PDE9A (0.37)	ADORA2AADORA1ALDH1A1HPGDKDM4E
	SCHEMBL21279076	0.89	ADORA2A (0.40)	KDM5BKDM4AADORA2AADORA1ALDH1A1
	SCHEMBL19908985	0.89	ALDH1A1 (0.42)	KDM5BKDM4AADORA2AADORA1ALDH1A1
	SCHEMBL19909422	0.88	PIP4K2A (0.40)	KDM5BKDM4AADORA2AADORA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.