SCHEMBL19909447

SCHEMBL19909447

Cc1cc(-c2c(-n3c4cc(-c5ccc(C(F)(F)F)cc5C(F)(F)F)ccc4c4ccc(-c5ccc(C(F)(F)F)cc5C(F)(F)F)cc43)cc(C#N)cc2-n2c3cc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)ccc3c3ccc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)cc32)cc(C)n1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 2/20 0.35
FEN1 P39748 2/20 0.35
CYP2C9 P11712 1/20 0.35
SCN9A Q15858 1/20 0.35
GRM5 P41594 2/20 0.33
DGAT1 O75907 1/20 0.32
SOAT1 P35610 1/20 0.32
KCNH2 Q12809 1/20 0.32
KIF11 P52732 1/20 0.32
NSD2 O96028 1/20 0.32
CRHR1 P34998 1/20 0.31
PSEN1 P49768 1/20 0.31
PSEN2 P49810 1/20 0.31
APH1B Q8WW43 1/20 0.31
NCSTN Q92542 1/20 0.31
APH1A Q96BI3 1/20 0.31
PSENEN Q9NZ42 1/20 0.31
AR P10275 2/20 0.31
MAT2A P31153 1/20 0.31
GRM2 Q14416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19913296 0.94 CYP2C9 (0.32) ALOX5APFEN1CYP2C9SCN9AGRM5
SCHEMBL22563579 0.91 ALOX5AP (0.35) ALOX5APFEN1CYP2C9SCN9AGRM5
SCHEMBL21414155 0.90 ALOX5AP (0.36) ALOX5APFEN1CYP2C9SCN9ADGAT1
SCHEMBL20617428 0.89 RXRA (0.38) ALOX5APFEN1CYP2C9SCN9ADGAT1
SCHEMBL19903686 0.89 ALOX5AP (0.36) ALOX5APFEN1CYP2C9SCN9ADGAT1
SCHEMBL19913276 0.89 GRM5 (0.38) GRM5DGAT1SOAT1KCNH2KIF11
SCHEMBL20112035 0.88 ALOX5AP (0.38) ALOX5APFEN1CYP2C9SCN9ADGAT1
SCHEMBL19942768 0.88 ALOX5AP (0.35) ALOX5APFEN1CYP2C9SCN9AGRM5
SCHEMBL22562412 0.87 CYP2C9 (0.37) ALOX5APFEN1CYP2C9SCN9AGRM5
SCHEMBL19919811 0.86 ALOX5AP (0.36) ALOX5APFEN1CYP2C9SCN9ADGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 ALOX5AP 2798/4885FEN1 2478/4885CYP2C9 102/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 ALOX5AP 3906/4885FEN1 1491/4885CYP2C9 1631/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 ALOX5AP 2798/4885FEN1 2478/4885CYP2C9 102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.