Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 3/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 3/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 3/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1992064 | 0.93 | PTGDR2 (0.39) | ABCC9ABCC8KCNJ11KCNJ8ABCB11 | |
| SCHEMBL14828506 | 0.82 | PTGDR2 (0.43) | ABCB11PTGDR2CNR1 | |
| SCHEMBL2907114 | 0.82 | PTGS2 (0.48) | ABCC9ABCC8KCNJ11KCNJ8ALOX5AP | |
| SCHEMBL1993598 | 0.81 | PTGDR2 (0.61) | PTGDR2ALOX5APFEN1 | |
| SCHEMBL1988641 | 0.80 | ABCB11 (0.50) | ABCC9ABCC8KCNJ11KCNJ8ABCB11 | |
| SCHEMBL2347649 | 0.80 | PTGDR2 (0.40) | ABCB11PTGDR2ALOX5APFEN1CTSA | |
| SCHEMBL1992062 | 0.78 | ABCB11 (0.49) | ABCC9ABCC8KCNJ11KCNJ8ABCB11 | |
| SCHEMBL1996728 | 0.78 | PPARG (0.42) | ABCC9ABCC8KCNJ11KCNJ8PTGDR2 | |
| SCHEMBL1990646 | 0.77 | POLB (0.44) | ABCC9ABCC8KCNJ11KCNJ8ALOX5AP | |
| SCHEMBL1992682 | 0.77 | PTGDR2 (0.37) | ABCC9ABCC8KCNJ11KCNJ8PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008350-B2 | Biphenyloxyacetic acid derivatives for the treatment of respiratory disease | ASTRAZENECA AB (SE) | 2011-08-30 | — | — | US | disclosed |
| US-20110152374-A1 | Biphenyloxyacetic Acid Derivatives for the Treatment of Respiratory Disease | ASTRAZENECA AB (SE) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152374-A1 | Biphenyloxyacetic Acid Derivatives for the Treatment of Respiratory Disease | BPGM, PPARA, HPD | ABCC9 1711/4885ABCC8 1805/4885KCNJ11 3890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.