Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | STAT1 | P42224 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22563772 | 0.92 | KDM4E (0.34) | ALDH1A1MAPTKDM4ENR1H4 | |
| SCHEMBL22564161 | 0.89 | NR1H4 (0.37) | ALDH1A1MAPTKDM4ENR1H4MEN1 | |
| SCHEMBL22563773 | 0.89 | KLKB1 (0.32) | ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL22564364 | 0.88 | KMT2A (0.34) | ALDH1A1MAPTKDM4EMEN1LMNA | |
| SCHEMBL22564091 | 0.88 | NR1H4 (0.38) | ALDH1A1MAPTKDM4ENR1H4GAA | |
| SCHEMBL22564153 | 0.87 | ALDH1A1 (0.33) | ALDH1A1MAPTNPC1LMNARAB9A | |
| SCHEMBL19909882 | 0.87 | NR1H4 (0.33) | ALDH1A1NR1H4NPC1LMNARAB9A | |
| SCHEMBL22564154 | 0.85 | NR1H4 (0.37) | ALDH1A1NR1H4MEN1NPC1LMNA | |
| SCHEMBL20844975 | 0.85 | MCHR1 (0.33) | NR1H4NPC1RAB9A | |
| SCHEMBL20844961 | 0.85 | P2RX7 (0.32) | ALDH1A1MAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |