Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19910455 | 0.88 | L3MBTL1 (0.50) | L3MBTL1ACHEMCHR1MEN1KMT2A | |
| SCHEMBL14569771 | 0.79 | TSHR (0.69) | ACHEMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL19910374 | 0.79 | KDM4E (0.46) | L3MBTL1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL9623610 | 0.78 | LMNA (0.66) | ALDH1A1THRATHRB | |
| SCHEMBL21574223 | 0.78 | L3MBTL1 (0.46) | L3MBTL1ACHEMCHR1MEN1KMT2A | |
| SCHEMBL229472 | 0.77 | MRGPRX4 (0.69) | MEN1KMT2A | |
| SCHEMBL2741671 | 0.77 | MCHR1 (0.62) | MCHR1THRATHRB | |
| SCHEMBL14569696 | 0.77 | TSHR (0.66) | ACHEMEN1KMT2AKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL224422 | 0.76 | MCHR1 (0.61) | MCHR1THRATHRB | |
| SCHEMBL1470380 | 0.76 | LMNA (0.63) | KMT2AALDH1A1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3065738-B1 | COMPOSITIONS AND METHODS FOR MODULATING FARNESOID X RECEPTORS | NOVARTIS AG (CH) | 2018-02-28 | — | — | EP | disclosed |