Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19910374 | 0.91 | KDM4E (0.46) | L3MBTL1KDM4EALDH1A1LTA4HSLC6A9 | |
| SCHEMBL21574223 | 0.90 | L3MBTL1 (0.46) | L3MBTL1KDM4EALDH1A1SLC6A9THRA | |
| SCHEMBL19910396 | 0.88 | L3MBTL1 (0.61) | L3MBTL1KDM4EALDH1A1THRATHRB | |
| SCHEMBL19910479 | 0.84 | LPAR1 (0.55) | KDM4EALDH1A1LTA4HMEN1KMT2A | |
| SCHEMBL28897893 | 0.83 | LPAR1 (0.43) | L3MBTL1KDM4ETHRATHRBLMNA | |
| SCHEMBL19910481 | 0.81 | KDM4E (0.62) | KDM4EALDH1A1LTA4HRAB9AACHE | |
| SCHEMBL2087136 | 0.77 | MAOB (0.64) | L3MBTL1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9623610 | 0.76 | LMNA (0.66) | ALDH1A1THRATHRBLMNAMAPK1 | |
| SCHEMBL2741671 | 0.75 | MCHR1 (0.62) | THRATHRBLMNAMAPK1HTT | |
| SCHEMBL2087020 | 0.75 | MEN1 (0.49) | KDM4EALDH1A1LTA4HTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3065738-B1 | COMPOSITIONS AND METHODS FOR MODULATING FARNESOID X RECEPTORS | NOVARTIS AG (CH) | 2018-02-28 | — | — | EP | disclosed |